SageneX Lab

Peptide drug discovery for muscle and beyond.

Precision oligopeptide discovery platform that combines phenotypic high-throughput screening, built-in target deconvolution, and off-target counterscreens in one workflow applicable to endless targets and indications.

Indication-agnostic platform

Built to discover peptide drugs across multiple therapeutic areas.

Muscle first

We start with muscle because the unmet need is large, readouts are clear, and the biology is highly actionable.

Powering AI

Our workflow generates structured functional biology data that AI systems can learn from.

WHY IT MATTERS

Muscle is our first wedge into a broader therapeutic platform

Frailty begins as muscle, bone, and joint function decline. Sarcopenia is a strong entry point: high unmet need, clear functional readouts, and no approved drug.

Instead of chasing a single pathway, SageneX maps secretome-inspired oligopeptides across phenotype, receptor context, and mechanism.

Fit older man lifting a barbell in a modern gym

OUR PLATFORM

One platform. Multiple therapeutic directions.

Each cycle links peptide libraries, receptor context, functional rescue, mechanism, and early safety signals into one discovery workflow.

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01

Build peptide libraries

Combinatorial oligopeptide libraries inspired by signaling biology.

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02

Screen peptide × receptor function

High-throughput screens measure rescue, growth, and functional response.

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03

Deconvolute mechanism

Built-in target deconvolution maps peptide-receptor-function relationships.

04

Counterscreen and prioritize

Early cardiac and off-target panels prioritize the strongest candidates.

FOCUS AREAS

We discover peptide drugs for muscle and beyond

Muscle is our first focus, with expansion potential across other peptide-responsive biology domains.

AI-BIO VALUE

Functional biology data that AI-bio labs can use

Our discovery workflow produces structured, mechanism-linked datasets that support internal programs and partnerable AI-bio collaborations.

Human-relevant phenotype data

Structured readouts that reflect function, not just static biomarkers.

Peptide-receptor-function maps

Peptides, receptors, and outcomes connected into actionable maps.

Safety-aware datasets

Counterscreens generate safety-relevant data for candidate prioritization.

Interested in peptide drugs for muscle and beyond?

Reach out for the deck, platform collaborations, or partnership discussions.