Less than 1% of peptides have been explored.
The world fishes one known target at a time.
We map the entire ocean.
Less than 1% of peptides have been explored.
The world fishes one known target at a time.
We map the entire ocean.
Comparison
Conventional approach
Target-Based Discovery
Bet everything on one target before you know it works.
- Need a known target to start
- Hit identification outside living biology — requires cell-based assay development
- One target, one shot — most never pan out. Risk of wasted years of research
1drug candidate3–5 years
SageneX Lab
Phenotypic Discovery
Find the expected therapeutic outcome, then reverse-engineer the mechanism of action.
- Target-agnostic — no known target required
- On-cell HIT discovery in a physiological environment — drastically reduced hit-to-lead optimization
- Multiple pairs of actionable targets and hits identified
100–200drug candidates6–12 months
